pubmed trends
http://pubmed.sekgen.xyz
Research trend analytics from 36M+ PubMed articles.
No API keys. No subscriptions.
Just pay per query with USDC.
x402 protocol MPP protocol Base L2 · Tempo USDC from $0.01/query
Read the docs →
$ awal x402 pay 'http://pubmed.sekgen.xyz/api/v1/trends?query=CRISPR'
# pays $0.01 USDC → returns trend data

{ "query": "CRISPR", "total_results": 48523,
  "analytics": { "cagr": 0.187, "trend_direction": "growing" } }

$ awal x402 pay 'http://pubmed.sekgen.xyz/api/v1/hottest-weekly?category=oncology'
# pays $0.05 USDC → this week's hottest topics

{ "hottest": [{ "term": "KRAS inhibitor", "spike_ratio": 1.48 }] }

$

Endpoints

/trends
Year-by-year publication counts and growth analytics
$0.01
/compare
Head-to-head trend comparison across multiple terms
$0.02
/emerging
Detect topics with accelerating publication rates
$0.05
/snapshot
Quick single-year publication count
$0.01
/pulse
7d / 30d / 90d activity with year-over-year change
$0.02
/hottest-weekly
This week's spiking topics ranked by surge ratio
$0.05
/keypapers
Scored key papers with PMIDs for MCP follow-up
$0.03
/digest
Key papers + MeSH terms + frequent authors
$0.08
/explore
Discover emerging signals across all categories
$0.10

Use cases

Weekly Research Monitor
A cron job that watches GLP-1 cardiology research and sends your team a briefing. Three calls, $0.10/week.
Science Due Diligence
Evaluate a biotech's scientific positioning in 4 API calls for $0.13.
Grant Writing Assistant
Help a PI build the Significance section with emerging trends and key papers. $0.19/grant.
Single-Call Lookups
One endpoint, one answer. What's hot in oncology? Who is Jennifer Doudna? $0.01--$0.05.

See all use cases with real data →

How payment works

1
Request — Your agent sends a normal HTTP GET. No auth headers needed.
2
402 response — Server responds with payment instructions: amount, asset, recipient.
3
Pay — Your client signs a USDC transfer and retries with proof. Protocol is chosen by the client via payment header.
4
Data — Server verifies payment, returns the data. Done.

•
x402 — USDC on Base L2. Use x402-compatible clients or Coinbase awal.
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MPP — USDC on Tempo. Use agentcash, the Tempo CLI, or any MPP-compatible client.

Built for agents

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Works with x402-compatible clients (USDC on Base) or MPP-compatible clients (USDC on Tempo)
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Responses are JSON — designed for LLMs and data pipelines, not dashboards
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Machine-readable docs at /llms.txt
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Pairs with Anthropic's PubMed MCP — trend to abstract in 3 calls

Data from NCBI PubMed. Full documentation · Powered by x402 + MPP · Base + Tempo